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Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise
Sponsor: McMaster University
Summary
The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.
Official title: The Effect of Ketone Monoester Supplementation and High Altitude on Exercising Cerebral Blood Flow
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
14
Start Date
2025-05-28
Completion Date
2025-08-31
Last Updated
2025-07-14
Healthy Volunteers
Yes
Conditions
Interventions
Ketone Monoester (KME)
0.6 g KME per kg body mass; \[R\]-3-hydroxybutyl \[R\]-3-hydroxybutyrate. (Delta G Ketone, TΔS, Oxford).
Placebo
Inert, calorie-free placebo drink that is taste-matched to the ketone monoester supplement
Locations (2)
Barcroft Research Station
Bishop, California, United States
University of Guelph
Guelph, Ontario, Canada