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RECRUITING
NCT07064005
PHASE1

Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.

Sponsor: Pravat Mandal

View on ClinicalTrials.gov

Summary

This study is designed l to evaluate the effects of GGC oral supplementation in early Parkinson's disease (PD) patients. The main objectives of the study are to evaluate: 1. To study the enrichment of master antioxidant, glutathione (GSH) levels in brain and blood of these PD patients compared to baseline due to GGC supplementation. 2. To study the changes in motor function, cognitive skills in PD patients due to GGC oral supplementation 3. To study impact of GGC on gut health on the PD patients.

Official title: Brain Glutathione (GSH) Enrichment Through Gamma-glutamylcysteine (GGC) Supplementation in Early Parkinson's Disease Patients for Reduction of Extrapyramidal Motor Disturbances and Halting Cognition Decline: A Pilot Trial

Key Details

Gender

All

Age Range

50 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2026-03-20

Completion Date

2027-11-27

Last Updated

2026-04-09

Healthy Volunteers

No

Interventions

DRUG

Gamma- glutamylcysteine

400 mg (two times) per day

Locations (1)

UPMC Presbyterian Hospital

Pittsburgh, Pennsylvania, United States