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Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions
Sponsor: Al-Azhar University
Summary
This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated caries-affected dentin and the influence of Er, Cr: YSGG Laser treatment.
Key Details
Gender
All
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
21
Start Date
2025-09-15
Completion Date
2026-09-15
Last Updated
2025-07-29
Healthy Volunteers
Yes
Conditions
Interventions
Curodont Repair Fluoride Plus (Self-assembling peptide remineralization agent)P11-4 peptide, fluoride, mild acidic buffer (pH ~4.5) , Credentis AG, Switzerland
Pretreatment with Curodont Repair Fluoride Plus (P11-4 + fluoride)
Beautifil II LS
Application of Giomer restorative material following standard adhesive procedures without pretreatment.