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New Insights Into the Biological Activity Evaluation of Mango Juices Processed by Sustainable Emerging Technologies
Sponsor: National Research Council, Spain
Summary
The aim of this clinical trial is to study the effect of a habitual dietary intake of commercial high pressure-processed (HPP) mango juice \[mango puree (20%)-orange juice (80%)\] or control juice \[water (20%)-HPP orange juice (80%)\]. There are numerous in vitro and in vivo animal studies that support exceptional health-promoting characteristics of mango products (pulp, peel, seed, juice, extracts, etc.) such as antidiabetic, anticancer, antiinflammatory, antioxidant and antibacterial activities based on their phytochemical composition, but there are many fewer studies assessing the absorption, metabolism, and health-related properties of phytochemical from commercial mango fruit juices (only 20% of mango pulp) in humans. Consequently, this study proposes for the first time the study of the effects of commercial HPP mango juice consumption on health biomarkers by a human intervention study. Researchers will compare the bioavailability (metabolite profiles) of compounds with health effects and the biomarkers of health to evaluate if mango juice works better that control juice.
Official title: New Insights Into the Development and Biological Activity Evaluation of Mango Juices Processed by Sustainable Emerging Technologies
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-06
Completion Date
2027-12
Last Updated
2025-07-16
Healthy Volunteers
No
Interventions
HPP mango juice group
During each intervention period, participants will be instructed to consume 500 mL of juice/day in two doses, 250 mL in the morning and 250 mL in the afternoon
control juice
During each intervention period, participants will be instructed to consume 500 mL of juice/day in two doses, 250 mL in the morning and 250 mL in the afternoon
Locations (1)
Institute of Food Science, Technology and Nutrition (ICTAN), National Research Council (CSIC)
Madrid, Madrid, Spain