Clinical Research Directory

Inclusion Criteria: \- (1) To voluntarily participate in the study, I or his legal representative signed a written informed consent. (2) 18-80 years old (including 18 and 80 years old), male. (3) in accordance with the indication of prostate biopsy. Exclusion Criteria: * (1) in the stage of acute genitourinary infection or fever. (2) patients with chronic pain (such as bone metastasis of prostate cancer, knee osteoarthritis, scapulohumeral periarthritis, etc.) or acute pain (tonsillitis, acute lumbar sprain, etc.) before surgery. (3) Continuous use of anti-anxiety or analgesic drugs (use of anti-anxiety drugs or analgesics for more than 1 week in the past 3 months). (4) in the decompensated stage of cardiac insufficiency; A disease with a tendency to bleed heavily. (5) severe immunosuppression. (6) hypertension, diabetes and other complications were poorly controlled or unstable. (7) complicated with severe internal or external hemorrhoids, perianal or rectal lesions, and anal stenosis. (8) perineal skin ulceration, infection, and abnormal skin sensation. (9) patients with serious psychological diseases or uncooperative puncture. (10) allergy to narcotic drugs and fear of acupuncture operators. (11) Participants who participated in other clinical trials within 3 months before enrollment. (12) other conditions considered by the investigator to be inappropriate to participate in the trial.