Clinical Research Directory

Inclusion Criteria: * To be between the ages of 40-69, * Baseline left ventricular ejection fraction (LVEF) \>50%, * Absence of coronary artery disease and haemodynamically significant valvular heart disease, * Absence of carotid atherosclerotic plaques, * Volunteering to participate in the research, * At least 15 months after breast cancer surgery, * No problems in reading and/or understanding the scales and being able to co-operate with the tests. * Physically inactive (60 minutes of structured exercise per week \<). Exclusion Criteria: * Presence of active infection, * Presence of bilateral breast cancer, * History of surgical, neurological or orthopaedic problems that may affect upper extremity functionality other than breast cancer surgery, * Having a neurological disease or other clinical diagnosis that may affect cognitive status, * Left ventricular dysfunction and severe liver and kidney dysfunction before starting chemotherapy * Musculoskeletal and neurological disease that may affect exercise performance, symptomatic heart disease, previous lung surgery and malignant disease. * Presence of unstable hypertension or diabetes mellitus.