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RECRUITING
NCT07075185
PHASE1

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

Sponsor: Kelonia Therapeutics, Inc.

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to evaluate the safety, tolerability, and recommended Phase 2 Dose (RP2D) of KLN-1010 in patients with relapsed or refractory multiple myeloma.

Official title: A Phase 1 Study to Evaluate the Safety of KLN-1010, a Novel, In Vivo Gene Therapy to Generate Anti-B Cell Maturation Antigen (Anti-BCMA) Chimeric Antigen Receptor-T Cells (CAR-T) in Patients With Relapsed and Refractory Multiple Myeloma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2025-07-16

Completion Date

2042-05

Last Updated

2026-04-07

Healthy Volunteers

No

Interventions

DRUG

KLN-1010

Given at specified dose one time

Locations (6)

City of Hope

Duarte, California, United States

Emory University Hospital

Atlanta, Georgia, United States

Providence Portland Medical Center

Portland, Oregon, United States

The Royal Prince Alfred

Camperdown, New South Wales, Australia

Peter MacCallum Cancer Centre

Melbourne, Victoria, Australia

The Alfred Paula Fox Melanoma and Cancer Centre

Melbourne, Victoria, Australia