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A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma
Sponsor: Kelonia Therapeutics, Inc.
Summary
The goal of this clinical trial is to evaluate the safety, tolerability, and recommended Phase 2 Dose (RP2D) of KLN-1010 in patients with relapsed or refractory multiple myeloma.
Official title: A Phase 1 Study to Evaluate the Safety of KLN-1010, a Novel, In Vivo Gene Therapy to Generate Anti-B Cell Maturation Antigen (Anti-BCMA) Chimeric Antigen Receptor-T Cells (CAR-T) in Patients With Relapsed and Refractory Multiple Myeloma
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-07-16
Completion Date
2042-05
Last Updated
2026-04-07
Healthy Volunteers
No
Conditions
Interventions
KLN-1010
Given at specified dose one time
Locations (6)
City of Hope
Duarte, California, United States
Emory University Hospital
Atlanta, Georgia, United States
Providence Portland Medical Center
Portland, Oregon, United States
The Royal Prince Alfred
Camperdown, New South Wales, Australia
Peter MacCallum Cancer Centre
Melbourne, Victoria, Australia
The Alfred Paula Fox Melanoma and Cancer Centre
Melbourne, Victoria, Australia