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Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy
Sponsor: Roswell Park Cancer Institute
Summary
This clinical trial studies whether transperineal micro-ultrasound can be used to detect prostate cancer during biopsy. Transrectal ultrasound is often used during prostate biopsy. Transrectal ultrasound imaging is a procedure in which a probe that sends out high-energy sound waves is inserted into the rectum. The sound waves are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissue called a sonogram. Transrectal ultrasound is used to look for abnormalities in the rectum and nearby structures, including the prostate. The images are used to guide the prostate biopsy. Transperineal micro-ultrasound is completed by placing a probe over the skin between the scrotum and anus (perineum). It is a high-resolution ultrasound at 29 megahertz (MHz) (compared to traditional ultrasound at 6-9 MHz). This higher frequency allows for an improved spatial resolution. This improved spatial resolution is approximately the diameter of a prostatic duct, and therefore, may be able to visualize slight changes in the structure of prostatic ducts that are not possible with standard transrectal ultrasound. Transperineal micro-ultrasound may be more effective in detecting prostate cancer during biopsy.
Official title: Investigating the Feasibility of Using Transperineal Micro-Ultrasound to Detect Clinically Significant Prostate Cancer
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
138
Start Date
2026-04-15
Completion Date
2027-01-15
Last Updated
2026-03-11
Healthy Volunteers
No
Conditions
Interventions
Biopsy of Prostate
Undergo standard of care prostate biopsy
Magnetic Resonance Imaging
Undergo MRI
Micro-ultrasound Imaging
Undergo transperineal micro-ultrasound imaging
Micro-ultrasound Imaging
Undergo transrectal micro-ultrasound imaging
Locations (1)
Roswell Park Cancer Institute
Buffalo, New York, United States