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NOT YET RECRUITING
NCT07075705
NA

Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy

Sponsor: Roswell Park Cancer Institute

View on ClinicalTrials.gov

Summary

This clinical trial studies whether transperineal micro-ultrasound can be used to detect prostate cancer during biopsy. Transrectal ultrasound is often used during prostate biopsy. Transrectal ultrasound imaging is a procedure in which a probe that sends out high-energy sound waves is inserted into the rectum. The sound waves are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissue called a sonogram. Transrectal ultrasound is used to look for abnormalities in the rectum and nearby structures, including the prostate. The images are used to guide the prostate biopsy. Transperineal micro-ultrasound is completed by placing a probe over the skin between the scrotum and anus (perineum). It is a high-resolution ultrasound at 29 megahertz (MHz) (compared to traditional ultrasound at 6-9 MHz). This higher frequency allows for an improved spatial resolution. This improved spatial resolution is approximately the diameter of a prostatic duct, and therefore, may be able to visualize slight changes in the structure of prostatic ducts that are not possible with standard transrectal ultrasound. Transperineal micro-ultrasound may be more effective in detecting prostate cancer during biopsy.

Official title: Investigating the Feasibility of Using Transperineal Micro-Ultrasound to Detect Clinically Significant Prostate Cancer

Key Details

Gender

MALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

138

Start Date

2026-04-15

Completion Date

2027-01-15

Last Updated

2026-03-11

Healthy Volunteers

No

Interventions

PROCEDURE

Biopsy of Prostate

Undergo standard of care prostate biopsy

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Micro-ultrasound Imaging

Undergo transperineal micro-ultrasound imaging

PROCEDURE

Micro-ultrasound Imaging

Undergo transrectal micro-ultrasound imaging

Locations (1)

Roswell Park Cancer Institute

Buffalo, New York, United States