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RECRUITING
NCT07076082
PHASE4

Vascular Trial Associated Registry Pilot

Sponsor: Corewell Health West

View on ClinicalTrials.gov

Summary

The purpose of this investigator-initiated, multicenter, open label, randomized trial is to evaluate 1 month vs. 6 months of dual antiplatelet therapy (DAPT) in patients undergoing lower extremity endovascular revascularization. We hypothesize that extending dual antiplatelet therapy (DAPT) to six months, compared to one month, will improve patency rates of target vessels following peripheral vascular intervention (PVI) without significantly increasing complications, particularly bleeding events.

Official title: Vascular Trial Associated Registry Pilot: Antiplatelet Therapies for Patients Undergoing Lower Extremity Endovascular Revascularization

Key Details

Gender

All

Age Range

45 Years - Any

Study Type

INTERVENTIONAL

Enrollment

350

Start Date

2025-10-15

Completion Date

2028-10-30

Last Updated

2026-01-07

Healthy Volunteers

No

Interventions

DRUG

Clopidogrel (Plavix) Pharmacogenetic Test Reagents

Dual antiplatelet therapy (DAPT), defined as the use of Clopidogrel (75 mg/day) (clopidogrel) and aspirin (81 mg or more/day). Single antiplatelet therapy (SAPT), defined as the use of aspirin (81 mg or more/day).

Locations (2)

Henry Ford Hospital

Detroit, Michigan, United States

Corewell Health

Grand Rapids, Michigan, United States