Clinical Research Directory

Inclusion Criteria: * Informed consent as documented by signature * ≥18 years at time of signing of informed consent * Acute ischemic stroke. * Stroke onset \< 7 days from randomization. * Contralateral, unilateral, incomplete upper limb paresis, incl. : * FMA-UE \< 63/66 * Residual voluntary finger extension (VFE) of \> 10 degrees Exclusion Criteria: * Pregnancy/lactation or positive pregnancy test in women of childbearing age * Pre-stroke handicap (mRS \> 2) * Diseases affecting motor function (e.g., Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS)) * Participation in another study with investigational medicinal product within 30 days preceding and during the present study * Enrolment of the investigator, his/her family members, employees, or other dependent persons * Known hypersensitivity to Maraviroc, Mannitol, peanuts, or soy * History of significant liver disease, hepatitis, elevated liver function tests (\> 1.5 upper limit of normal) * History of significant renal disease or End Stage Renal Disease/dialysis, acute renal injury, Creatinine Clearance (CrCl \< 30ml/min/1.73m2) * Patients with cardiovascular comorbidities and risk for orthostatic hypotension * HIV infection * Concomitant use of strong CYP3A4 inhibitors or inducers