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A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension
Sponsor: Zhejiang University
Summary
This study is a prospective, single-center, randomized controlled trial focusing on patients with acute necrotizing pancreatitis (ANP) complicated by pancreatic sinistral portal hypertension (PSPH). The study aims to study the impact of total splenectomy on the debridement efficacy, perioperative recovery, and prognosis of patients with ANP complicated by PSPH.
Official title: The Impact of Splenectomy on Debridement Efficacy, Perioperative Recovery, and Prognosis in Patients With Acute Necrotizing Pancreatitis Complicated by Pancreatic Sinistral Portal Hypertension
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2025-07-30
Completion Date
2028-02-29
Last Updated
2025-07-23
Healthy Volunteers
No
Interventions
Splenectomy
Open Debridement combined with distal pancreatectomy and total splenectomy
Control
Open Debridement alone
Locations (1)
First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China