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Observational Study on APL-like aCute Myeloid Leukemia: disTInct Phenotype and Early VAscular complicaTions
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto
Summary
This is a multicenter observational study with a retrospective and a prospective cohort investigating clinically and biologically the APL-like subset as a potential predictor of coagulopathy and susceptibility to early vascular events.
Official title: Observational Study on APL-like Subset Within NPM1-mutated Acute Myeloid Leukemia: a Distinct Phenotypic Signature Correlating With Early-onset Vascular Complications. ACTIVATE (APL-like aCute Myeloid Leukemia: disTInct Phenotype and Early VAscular complicaTions)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
220
Start Date
2026-07
Completion Date
2028-11
Last Updated
2026-06-22
Healthy Volunteers
No
Conditions
Interventions
observation of incidence of early vascular events
observation of difference incidence of early vascular events in the two cohorts
Locations (1)
SOD Ematologia, Università di Firenze, AOU Careggi
Florence, Italy