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ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer
Sponsor: West China Hospital
Summary
Radiation dermatitis is a common complication in head and neck squamous cell carcinoma patients receiving radiotherapy. This study proposes an ROS-scavenging amino acid-based nanolipid to prevent oxidative skin damage. A multicenter randomized trial will evaluate its safety and efficacy in reducing dermatitis severity and improving treatment continuity.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-07-23
Completion Date
2025-11-23
Last Updated
2025-09-10
Healthy Volunteers
No
Conditions
Interventions
Amino acid-derived lipids
Amino acid-derived lipids are applied to the treatment area, once daily during radiotherapy.
standard of care
Standard of care
Locations (1)
West China Hospital, Sichuan University
Chengdu, Sichuan, China