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Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients
Sponsor: Weizmann Institute of Science
Summary
This observational, multi-center study aims to collect data in order to develop a novel, minimally invasive diagnostic tool for MDS based on peripheral blood profiling of circulating hematopoietic stem and progenitor cells (cHSPCs) using single-cell RNA sequencing and DNA sequencing.
Official title: Development of a Peripheral Blood Assay to Replace BM Evaluation in Cytopenia - a Multi-Center Observational Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1500
Start Date
2025-06-01
Completion Date
2028-12
Last Updated
2026-03-25
Healthy Volunteers
No
Interventions
PERIBLOOD-MDS
In the study, peripheral blood will be taken from all patients, shipped and analyzed at the Weizmann Institute of Science to produce a report based on our technology. The report will contain data on the diagnosis, blast counts and karyotype. This information will be compared with the results from the bone marrow scan, taken separately to each patient, to validate the accuracy of our technology
Locations (2)
University of California San Diego
San Diego, California, United States
University of Miami
Miami, Florida, United States