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RECRUITING
NCT07081087

Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients

Sponsor: Weizmann Institute of Science

View on ClinicalTrials.gov

Summary

This observational, multi-center study aims to collect data in order to develop a novel, minimally invasive diagnostic tool for MDS based on peripheral blood profiling of circulating hematopoietic stem and progenitor cells (cHSPCs) using single-cell RNA sequencing and DNA sequencing.

Official title: Development of a Peripheral Blood Assay to Replace BM Evaluation in Cytopenia - a Multi-Center Observational Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1500

Start Date

2025-06-01

Completion Date

2028-12

Last Updated

2026-03-25

Healthy Volunteers

No

Conditions

Interventions

DIAGNOSTIC_TEST

PERIBLOOD-MDS

In the study, peripheral blood will be taken from all patients, shipped and analyzed at the Weizmann Institute of Science to produce a report based on our technology. The report will contain data on the diagnosis, blast counts and karyotype. This information will be compared with the results from the bone marrow scan, taken separately to each patient, to validate the accuracy of our technology

Locations (2)

University of California San Diego

San Diego, California, United States

University of Miami

Miami, Florida, United States