Clinical Research Directory

Common inclusion criteria for Group A and Group B: 1. Male or female, age above or equal to 18 years at the time signing informed consent. 2. Body mass index (BMI) more than or equal to (≥) 30 kilogram per meter square (kg/m\^2) with at least one of the following diagnosed obesity-related comorbidities: arterial hypertension, pre-diabetes, Obstructive Sleep Apnea (OSA) or coronary heart disease, chronic heart failure, or BMI ≥35 kg/m\^2. 3. History of at least one self-reported unsuccessful attempt to lose weight. 4. Capable of completing informed consent. Additional inclusion criteria for Group A: 1. The decision to initiate treatment with commercially available Wegovy has been made by the participant and the treating physician before and independently from the decision to include the participant in this study. 2. Initiation of treatment is not modified in any case due to participant's participation in the study. Common exclusion criteria for Group A and Group B: 1. Previous participation in this study (participation is defined as having given informed consent in this study) 2. Treatment with an investigational drug within 30 days prior to enrolment into the study. 3. Participant has had a prior serious allergic reaction to semaglutide or any of the ingredients in Wegovy. 4. Women with pregnancy or breast-feeding. 5. Women of childbearing potential and not using an adequate contraceptive method. 6. Men and women in their pregnancy attempts. 7. Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation. 8. History of any Glucagon-like peptide-1 (GLP-1) treatment within 180 days. 9. History of type 1 or type 2 diabetes mellitus.