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Physical Fitness and Hot Executive Function in Alzheimer's Risk
Sponsor: National Taiwan Normal University
Summary
This 18-month study tracks how physical fitness relates to executive function in older adults, aiming to determine if fitness improvements predict better cognitive performance. Participants complete assessments at baseline and 18 months, including cardiorespiratory fitness (YMCA bike test), muscle strength (chest and leg press tests), and executive function (computer tasks with brain activity recording via EEG). Additional measures include physical activity questionnaires, cognitive screening (MMSE), memory tests (digit span), demographics (age, sex, education), and blood tests for APOE ε4 gene status. No exercise program will be provided, allowing observation of natural fitness-cognition relationships in daily life.
Key Details
Gender
All
Age Range
50 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
240
Start Date
2025-01-10
Completion Date
2027-07-31
Last Updated
2025-07-23
Healthy Volunteers
Yes
Interventions
observation alone
No interventions will be conducted during the observation period, maintaining participants' normal daily living conditions.
Locations (1)
National Taiwan Normal University
Taipei, Taiwan