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Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Sponsor: University Hospital, Bordeaux
Summary
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications. Little is known about the determinants of severity in UC. The investigators hypothesize that distinct severity phenotypes of UC arise from intricated host-microbiota mechanisms influencing repair mechanisms. Our first and main objective is to study the natural history of UC during a one-year time period in a cohort of patients.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2025-09
Completion Date
2027-09
Last Updated
2025-07-24
Healthy Volunteers
No
Interventions
Blood sample
3 blood samples
biopsy
3 pairs of biopsy realised during the coloscopy
Locations (1)
CHU de Bordeaux
Pessac, France