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RECRUITING
NCT07085325

CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation

Sponsor: St. Jude Children's Research Hospital

View on ClinicalTrials.gov

Summary

The study is being done to learn more about the long-term health and well-being of participants treated for medulloblastoma. The study is to decide which evaluations focusing on therapy-related lasting effects (or toxicities) should be considered. Medulloblastoma outcomes have improved with contemporary therapies including modern neurosurgical techniques and risk-adapted radiotherapy and chemotherapy regimens. However, survivors remain at risk for long-term health problems such as neurocognitive deficits, hearing loss, impaired cardiorespiratory fitness and physical performance, cardiac and neuroendocrine dysfunction, musculoskeletal conditions, and infertility.

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

184

Start Date

2026-03

Completion Date

2031-10

Last Updated

2026-01-20

Healthy Volunteers

No

Conditions

Locations (1)

St. Jude Children's Research Hospital

Memphis, Tennessee, United States