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RECRUITING
NCT07086118
NA

Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery

Sponsor: Alexandria University

View on ClinicalTrials.gov

Summary

Postoperative nausea and vomiting (PONV) is a common consequence of ambulatory surgery, affecting up to 80% of high-risk patients and 20-30% overall. Despite being widespread, a prior survey found that patients are more averse to PONV than pain and other significant postoperative problems. Furthermore, even mild cases of PONV can have serious repercussions, such as postanesthesia care unit (PACU) workflow disruption, delayed discharges, higher medical costs, and lower patient satisfaction.PONV following intraocular surgery can be unpleasant and may lead to serious complications including suprachoroidal hemorrhage (SCH). SCH is a potentially serious condition that occurs when the posterior ciliary arteries or vortex veins burst, resulting in blood in the suprachoroidal region. The hypothesis is that dexamethasone will lower the incidence of PONV after cataract surgery when compared with metoclopramide.

Official title: Efficacy of Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery: A Double-blind Randomized Controlled Study

Key Details

Gender

All

Age Range

40 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

210

Start Date

2025-05-01

Completion Date

2025-12-01

Last Updated

2025-07-25

Healthy Volunteers

No

Interventions

OTHER

0.9% normal saline

patients in group P will receive 0.9% normal saline

DRUG

Metoclopramide 10mg

patients in group M will receive 10 mg metoclopramide

DRUG

Dexamethasone

patients in group D will receive 8 mg dexamethasone

Locations (1)

Alexandria University

Alexandria, Egypt