Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Predict Recompensation in Patients With Decompensated Cirrhosis Using Spleen Stiffness and Simple Blood Tests
Sponsor: Beijing Friendship Hospital
Summary
The goal of this observational study is to learn if spleen stiffness and other non-invasive markers can help predict recompensation in people with decompensated cirrhosis who are receiving effective treatment for the cause of their liver disease. The main questions it aims to answer are: * Can spleen stiffness and blood test results predict who will get better and stay better after cirrhosis becomes worse? * What are the features of people who recover after decompensation? Participants will: * Be people with decompensated cirrhosis who are already getting effective treatment (such as antiviral therapy or alcohol abstinence) * Be followed over time to check if they remain stable or have more liver problems * Have non-invasive tests done, including spleen stiffness measurement and blood tests Researchers will track how many participants recover and stay recovered over time, and use that information to build a tool to help predict outcomes in others with cirrhosis.
Official title: Prediction of Recompensation and Stable Recompensation in Patients With Decompensated Cirrhosis Using Spleen Stiffness Combined With Non-Invasive Markers: A Prospective, Observational, Multicenter Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
735
Start Date
2025-07-15
Completion Date
2028-12-30
Last Updated
2025-07-25
Healthy Volunteers
No
Conditions
Locations (28)
Beijing Ditan Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Beijing You'an Hospital, Capital Medical University
Beijing, Beijing Municipality, China
The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, China
Mengchao Hepatobiliary Hospital of Fujian Medical University
Fuzhou, Fujian, China
The Second Hospital of Lanzhou University
Lanzhou, Gansu, China
Foshan Traditional Chinese Medicine Hospital
Foshan, Guangdong, China
The First People's Hospital of Foshan
Foshan, Guangdong, China
Guangzhou Eighth People's Hospital
Guangzhou, Guangdong, China
Guangdong Provincial Hospital of Chinese Medicine
Guangzhou, Guangdong, China
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
Panyu Central Hospital
Guangzhou, Guangdong, China
The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai
Zhuhai, Guangdong, China
Guizhou Provincial People's Hospital
Guiyang, Guizhou, China
Taihe Hospital, Shiyan
Shiyan, Hubei, China
Hunan Provincial People's Hospital
Changsha, Hunan, China
Xiangya Hospital, Central South University
Changsha, Hunan, China
Nanjing Second Hospital
Nanjing, Jiangsu, China
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
The First Affiliated Hospital of China Medical University
Shenyang, Liaoning, China
Qingdao Municipal Hospital
Qingdao, Shandong, China
Huadong Hospital, Fudan University
Shanghai, Shanghai Municipality, China
Shanghai Public Health Clinical Center
Shanghai, Shanghai Municipality, China
Changzhi People's Hospital
Changzhi, Shanxi, China
Jincheng People's Hospital
Jincheng, Shanxi, China
Jinzhong People's Hospital
Jinzhong, Shanxi, China
The First Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
The Second Hospital of Shanxi Medical University
Taiyuan, Shanxi, China