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RECRUITING
NCT07087262
PHASE1

A Phase I Study of SNH-119014 in Healthy Volunteers

Sponsor: ScinnoHub Pharmaceutical Co., Ltd.

View on ClinicalTrials.gov

Summary

SNH-119014 is an oral small-molecule agonist of pyruvate kinase red blood cell isozyme (PKR) being developed for the treatment of hemolytic anemias. This initial study will characterize the safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of a single ascending dose and multiple ascending doses of SNH-119014 in the context of Phase 1 studies in healthy volunteers. The effects of food on the absorption of SNH-119014 will also be evaluated in healthy volunteers.

Official title: A Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic of SNH-119014 in Healthy Adult Volunteers

Key Details

Gender

All

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

96

Start Date

2025-06-27

Completion Date

2026-03-28

Last Updated

2025-07-25

Healthy Volunteers

Yes

Interventions

DRUG

SNH-119014

study drug

DRUG

Placebo

placebo

Locations (1)

The Second Hospital of Anhui Medical University

Hefei, Anhui, China