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A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy
Sponsor: Novartis Pharmaceuticals
Summary
This CML disease registry (ASC4REAL-2) aims to gather evidence on the tolerability, safety, effectiveness, and patient-reported outcomes (PRO) in real-world healthcare from patients with Ph+-CML-CP treated with TKIs approved for 1L and 2L, including prospective follow-up for 5 years identifying and describing long-term treatment outcomes.
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2025-12-17
Completion Date
2033-04-20
Last Updated
2026-06-25
Healthy Volunteers
No
Interventions
TKIs
There is no treatment allocation for NIS trials. Patients administered TKI (asciminib, bosutinib, dasatinib, imatinib, nilotinib) by prescription will be enrolled.
Locations (15)
University of Alabama at Birmingham
Birmingham, Alabama, United States
Stockton Hematology Oncology Medical Group Inc
Stockton, California, United States
Lundquist Inst BioMed at Harbor
Torrance, California, United States
Stamford Hospital
Stamford, Connecticut, United States
Sacred Heart Medical Oncology
Pensacola, Florida, United States
St Agnes Hospital
Baltimore, Maryland, United States
NY Cancer and Blood Specialists
East Setauket, New York, United States
SUNY Upstate Medical University
Syracuse, New York, United States
Tri-County Hematology and Oncology Associates
Canton, Ohio, United States
Oregon Oncology Specialists Salem
Salem, Oregon, United States
Avera Cancer
Sioux Falls, South Dakota, United States
Baylor Scott and White Research
Temple, Texas, United States
Fred Hutchinson Cancer Research Center
Seattle, Washington, United States
MultiCare Health System Institute
Tacoma, Washington, United States
Northwest Medical Specialties
Tacoma, Washington, United States