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Understanding Freezing of Gait Using Brain Signals and Virtual Reality
Sponsor: University of California, Los Angeles
Summary
Freezing of gait - the inability to start or continue walking - is a particularly disabling problem in Parkinson's disease that has few treatment options. This project records human brain activity from deep brain stimulation (DBS) devices during walking and freezing of gait episodes to understand the pathophysiology of freezing of gait. Findings will lay the foundation for the development of new treatment strategies that address this disabling symptom.
Official title: Leveraging Invasive Recordings and Immersive Virtual Reality to Characterize Freezing of Gait Mechanisms in Parkinson Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2025-11-01
Completion Date
2030-03
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
VR Freezing Task
Walking overground in immersive virtual reality (VR) environments that provoke freezing episodes
Dual Task
Walking overground with and without concomitant performance of secondary cognitive or motor task
External Cueing
Walking overground in immersive virtual reality (VR) environments that provoke freezing episodes with and without addition of visual and auditory cues.
Locations (1)
University of California, Los Angeles
Los Angeles, California, United States