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RECRUITING
NCT07093463
NA

Colon-delivered Riboflavin and Gut Microbiota Composition

Sponsor: dsm-firmenich Switzerland AG

View on ClinicalTrials.gov

Summary

Recent studies suggest B-vitamins such as riboflavin to possess prebiotic-like effects. However, there is still a lack of understanding of the exact host health benefits vs. conventional systemically available vitamin forms. The present study explores the benefit of colon-delivered vitamin B2 vs. conventional vitamin B2 in comparison to placebo in an aging population on gut microbiota and metabolic activity as well as gut health.

Official title: The Benefit of Colon-delivered Riboflavin (Riboflavin-cd) vs. Conventional Riboflavin on Gut Microbiota Composition and Metabolic Output in Healthy Aging Subjects - a Pilot Proof of Concept Study

Key Details

Gender

All

Age Range

50 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2025-07-18

Completion Date

2026-09

Last Updated

2026-03-19

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Colon-delivered riboflavin

10 mg of colon-delivered riboflavin

DIETARY_SUPPLEMENT

Conventional riboflavin

10 mg of conventional riboflavin

OTHER

Microcrystalline Cellulose

10 mg microcrystalline cellulose

Locations (1)

analyze & realize GmbH

Berlin, State of Berlin, Germany