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Comparison Between Carbapenems and Noncarbapenem Beta-lactam Antibiotics in Septic Burn Patients
Sponsor: Ain Shams University
Summary
The aim of this work is to evaluate the efficacy associated with Meropenem(example of carbapenems) as initial therapy for sepsis in burn patients compared with Pipracillin/Tazobactam (example of non carbapenem beta lactam antibiotics).
Official title: Comparison Between Carbapenems and Noncarbapenem Broad Spectrum Beta-lactam Antibiotics as Initial Antibiotic Therapy Against Sepsis in Burn Patients: A Prospective Study
Key Details
Gender
All
Age Range
21 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2024-01-01
Completion Date
2026-03-01
Last Updated
2025-10-03
Healthy Volunteers
No
Conditions
Interventions
Meropenem I.V. 2g as a 3 hour infusion every 8 hours
Non C group will receive non Carbapenems (Tazocin) 4.5 gm IV slow infusion over 20 minutes every 8 hours per day
Tazocin (pipercillin/tazobactam)
Non C group will receive non Carbapenems (Tazocin) 4.5 gm IV slow infusion over 20 minutes every 8 hours per day
Locations (1)
Ain Shams University Hospitals
Cairo, Egypt