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ACTIVE NOT RECRUITING
NCT07096310
PHASE1/PHASE2

Comparison Between Carbapenems and Noncarbapenem Beta-lactam Antibiotics in Septic Burn Patients

Sponsor: Ain Shams University

View on ClinicalTrials.gov

Summary

The aim of this work is to evaluate the efficacy associated with Meropenem(example of carbapenems) as initial therapy for sepsis in burn patients compared with Pipracillin/Tazobactam (example of non carbapenem beta lactam antibiotics).

Official title: Comparison Between Carbapenems and Noncarbapenem Broad Spectrum Beta-lactam Antibiotics as Initial Antibiotic Therapy Against Sepsis in Burn Patients: A Prospective Study

Key Details

Gender

All

Age Range

21 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2024-01-01

Completion Date

2026-03-01

Last Updated

2025-10-03

Healthy Volunteers

No

Conditions

Interventions

DRUG

Meropenem I.V. 2g as a 3 hour infusion every 8 hours

Non C group will receive non Carbapenems (Tazocin) 4.5 gm IV slow infusion over 20 minutes every 8 hours per day

DRUG

Tazocin (pipercillin/tazobactam)

Non C group will receive non Carbapenems (Tazocin) 4.5 gm IV slow infusion over 20 minutes every 8 hours per day

Locations (1)

Ain Shams University Hospitals

Cairo, Egypt