Clinical Research Directory

Inclusion Criteria: 1. ≥19 years of age 2. Patients diagnosed with functional dyspepsia according to the Rome IV criteria, who can be classified as having postprandial distress syndrome * Rome IV criteria for functional dyspepsia: 1. One or more of the following symptoms: 1. Uncomfortable postprandial fullness 2. Early satiation 3. Epigastric pain 4. Epigastric burning 2. No evidence of structural disease that could explain the symptoms * Symptoms must have started at least 6 months before diagnosis and been present during the last 3 months 3. No history of gastrointestinal surgery 4. No organic lesions found on upper endoscopy within the past 3 months 5. Voluntarily signed informed consent to participate in this clinical trial Exclusion Criteria: 1. Patients with confirmed structural diseases on upper gastrointestinal endoscopy, such as esophageal stricture, ulcer stricture, esophagogastric varices, Barrett's esophagus, active peptic ulcer, gastrointestinal bleeding, or eosinophilic esophagitis 2. Patients who have undergone surgery involving the esophagus, stomach, or duodenum 3. Patients with abnormal values in blood chemistry tests within the past month: * Total bilirubin, creatinine \> 1.5 times the upper limit of normal (ULN) * AST, ALT, alkaline phosphatase, BUN \> 2 times the ULN 4. Patients with diabetic gastroparesis 5. Patients with a history of drug or alcohol abuse within the past year 6. Pregnant or breastfeeding women -Patients currently taking medications that may affect the evaluation of the investigational drug's efficacy (e.g., acid-suppressing agents including PPIs, prokinetics, NSAIDs, anticholinergics, corticosteroids, antidepressants, erythromycin, mirtazapine, etc.) may only participate after a minimum 2-week wash-out period 7. Any other conditions that the investigator deems make the patient unsuitable for participation in the study