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RECRUITING
NCT07098156

Neural Correlates of Autistic Individuals With Anorexia Nervosa

Sponsor: University of Aberdeen

View on ClinicalTrials.gov

Summary

Masking is a behaviour or strategy used by many Autistic people to appear non-Autistic and blend in with a neurotypical society. The goal of this observational study is to understand the relationship between masking, anorexia nervosa symptoms and brain structure in Autistic people. The main questions this study aims to answer are: * Do Autistic individuals with anorexia nervosa show differences in structure or function of the brain relation to Autistic individuals without anorexia nervosa? * Do Autistic individuals with anorexia nervosa display higher levels of masking than Autistic individuals without anorexia nervosa? * Are there indeed relationships between levels of masking, anorexia nervosa symptoms and brain structure in Autistic people? Researchers will compare Autistic people without anorexia nervosa to Autistic people with anorexia nervosa to see if there are differences between groups. Participants will: * Complete a series of questionnaires focused on eating disorder symptoms, autistic traits, autistic masking and psychological well-being * Undergo an MRI scan at the Aberdeen Royal Infirmary

Official title: Neuroanatomical Differences Associated With Anorexia Nervosa and Masking Behaviour in Autistic Individuals

Key Details

Gender

All

Age Range

25 Years - 45 Years

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2025-07

Completion Date

2026-01

Last Updated

2025-08-01

Healthy Volunteers

No

Interventions

OTHER

Single Research Visit 3T MRI Research Scan

Single research visit scan performed with a 3T magnetic resonance imaging scanner.

OTHER

Demographic and Behavioural Questionnaires

A series of demographic and behavioural questionnaires to be completed by participants, either online or during the single study visit. Questionnaires include the Eating Disorder Examination Questionnaire, Autism Spectrum Quotient, Monotropism Questionnaire, Camouflaging Autistic Traits Questionnaire, Hospital Anxiety and Depression Scale, Adult Attention Deficit Hyperactivity Disorder Self-Report Scale, Work and Social Adjustment Scale, International Trauma Questionnaire and Leibowitz Social Anxiety Scale. These questionnaires will also include a demographic questionnaire to acquire measures such as age, BMI, co-occurring conditions, etc.

Locations (2)

Lilian Sutton Building

Aberdeen, Aberdeen City, United Kingdom

NHS Grampian Eating Disorder Services

Aberdeen, Aberdeen City, United Kingdom