Clinical Research Directory

Inclusion Criteria: * Subjects over 18 years old; * Subjects who have given their consent and signed an informed, free and express consent form; * Subjects with diagnosed ALS; * Subjects affiliated to or benefiting from a social security scheme. Exclusion Criteria: * Subjects with contraindications to the collection of biological samples (blood, skin, urine). * Subjects undergoing treatment likely to affect hemostasis (anticoagulants, platelet anti-aggregants, etc.) in the month prior to inclusion and during the study; * Subjects with hereditary or acquired haemostasis disorders; * Subjects who have undergone physical treatment (radiotherapy, etc.) on the area to be biopsied in the last 6 months; * Lidocaine-intolerant subjects; * Subjects who have reached the age of majority and are subject to a protective measure or are unable to express their consent.