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Singapore Population Research on Integrated exposoMe & Early Menopause
Sponsor: Institute for Human Development and Potential (IHDP), Singapore
Summary
Brief Summary The goal of this observational study is to learn how environmental factors, lifestyle choices, and social conditions affect the timing of menopause in Asian women aged 40-50 years living in Singapore. The main aims of the project are the following: * Do environmental pollutants and lifestyle exposures contribute to earlier menopause in Asian women? * What biological changes occur when women are exposed to harmful environmental factors during menopause transition? Participants will be followed for 18 months and will complete questionnaires about their health history, lifestyle, diet, and environmental exposures. Participants will provide blood, urine, stool, hair, and nail samples for laboratory analysis and undergo basic health assessments including weight, blood pressure, and bone density measurements. Participants will wear activity monitors and air pollution sensors for 7 days and attend follow-up visits at 6 months, 12 months, and 18 months to track changes in their health. This data will be obtained during the baseline visit.
Official title: From Exposome to Health Outcomes: A Population-Based Approach to Understanding and Mitigating Early Menopause in Singapore's Diverse Communities
Key Details
Gender
FEMALE
Age Range
40 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2025-08-06
Completion Date
2028-04-01
Last Updated
2025-08-03
Healthy Volunteers
Yes