Clinical Research Directory

Inclusion Criteria: Patients with pathological myopia and diffuse choroidal atrophy (DCA, Cat. 2 Meta PM) * Age ≥ 18 years and ≤ 55 years; * Patient consenting to be included in the study; * Examination and follow-up in at least one of the participating centers; * Severe pathological myopia with an axial length ≥ 26.5 mm in both eyes; * Presence of diffuse atrophy (category 2 of the Meta-PM classification) in the better eye; * Affiliated with or covered by a social security system. Pathological myopic patients with patch choroidal atrophy (PCA, Cat. 3 Meta PM): * Age ≥ 18 years and ≤ 55 years; * Patients who consent to be included in the study; * Examination and follow-up at least one of the participating centers; * High myopia with an axial length ≥ 26.5 mm in both eyes; * Presence of patch atrophy (category 3 of the Meta-PM classification) in the better eye; * Affiliated with or beneficiary of a social security system. Exclusion Criteria: * Identified genetic syndromic myopia, including Stickler syndromes type 1 and 2 (collagen 2A1 and 11A1), Marfan syndrome (fibrillin), Ehler-Danlos syndrome type 4 (lysyl-protocollagen hydroxylase), and Knobloch syndrome (collagen 18A). * Patient unwilling to participate or be followed up at one of the participating centers. * Binocular visual acuity ≥ 1 logMar (\<0.1 on the decimal scale). * Media opacities preventing quality imaging, including cataracts. * Patients benefiting from legal protection measures. * Pregnant or breastfeeding women. * Individuals who may not be able to tolerate the driving simulator.