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RECRUITING
NCT07101250
PHASE4

Preoperative Acetazolamide

Sponsor: Prisma Health-Upstate

View on ClinicalTrials.gov

Summary

The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.

Official title: Preoperative Acetazolamide for Improved Pain Control Following Laparoscopic Hysterectomy

Key Details

Gender

FEMALE

Age Range

21 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2025-10-30

Completion Date

2026-11-01

Last Updated

2026-02-20

Healthy Volunteers

No

Interventions

DRUG

Acetazolamide 500 MG Extended Release Oral Capsule

Active Drug

DRUG

Placebo

Inactive Drug

Locations (1)

Prisma Health

Greenville, South Carolina, United States