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A Prediction Model in Pregnant Women With Aplastic Anemia
Sponsor: Peking University People's Hospital
Summary
Aplastic anemia (AA) is a rare haematologic disorder characterized by bone marrow failure and pancytopenia. Its occurrence during pregnancy is exceedingly rare but poses significant risks, including maternal hemorrhage, infections, and perinatal complications such as preterm birth and fetal growth restriction. Consequently, pregnancy with AA is highly perilous for both mothers and infants. Early management is critical to ensure the health of both the mother and the baby. However, there are currently no predictive tools available to assess adverse outcomes in pregnant women with AA. Our center plans to conduct a multicenter, combined retrospective and prospective cohort study.
Official title: Development and Validation of a Prediction Model for Adverse Pregnancy Outcomes in Women With Aplastic Anemia
Key Details
Gender
FEMALE
Age Range
20 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2025-11-27
Completion Date
2030-12-31
Last Updated
2025-12-01
Healthy Volunteers
No
Conditions
Interventions
A combined retrospective and prospective observational follow-up
A combined retrospective and prospective observational follow-up
Locations (1)
Peking University People's Hospital
Beijing, China