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Autonomic Neural Blockade in Bariatric Surgery
Sponsor: Endeavor Health
Summary
The purpose of this research is to evaluate if autonomic nerve block (ANB- blocking pain and nausea signals) decreases pain and anti-nausea medication requirements as well as the experience of pain/nausea during the first 72 hours after sleeve gastrectomy or gastric bypass surgery. Participants will be randomly assigned either to the standard of care or the ANB group before surgery. As part of standard of care, in both groups, laparoscopic bariatric surgery will be initiated with local anesthetic injected into the abdominal wall. In the ANB group, participants will be given an additional injection of local anesthetic medication to block nerves on and around the stomach.
Official title: Autonomic Neural Blockade During Sleeve Gastrectomy and Gastric Bypass: A Randomized Controlled Trial Evaluating Pain and Nausea After Bariatric Surgery
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-03
Completion Date
2027-12
Last Updated
2026-01-29
Healthy Volunteers
No
Conditions
Interventions
Intraoperative autonomic neural blockade (ANB)
Local anesthetic block of the neurovascular tissue along the lesser curve of the stomach and celiac trunk during sleeve gastrectomy or gastric bypass surgery.
Laparoscopic Standard of Care Abdominal Wall Block
Administration of local anesthetic to abdominal incisions (standard of care)
Locations (1)
Endeavor Health
Evanston, Illinois, United States