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RECRUITING
NCT07105358
NA

Visual Plasticity Following Brain Lesions

Sponsor: Georgetown University

View on ClinicalTrials.gov

Summary

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.

Official title: Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-07-17

Completion Date

2028-06-30

Last Updated

2025-08-05

Healthy Volunteers

No

Interventions

DEVICE

transcranial random noise stimulation (tRNS)

Stimulation location: bilateral human middle temporal complex (hMT+). Stimulation parameters: 1 mA current intensity, with a frequency range of 101-640 Hz.

DEVICE

Sham Stimulation

Stimulation location: bilateral human middle temporal complex (hMT+). Stimulation parameters: Ramp up stimulation at 1mA with a frequency range of 101-640Hz for the first 30 seconds followed by no current for the remainder of the duration.

BEHAVIORAL

Perceptual learning-based training

A motion discrimination task, judging the global direction of moving dot stimuli with two different coherence levels.

Locations (1)

Georgetown University Medical Center

Washington D.C., District of Columbia, United States