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Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit
Sponsor: Stanford University
Summary
Evidence demonstrates that the risks of red blood cell transfusions outweigh benefits in many patients who are hospitalized in the pediatric intensive care unit with increased risk of organ dysfunction, infection, delirium, and death. Recommendations have been developed to restrict transfusion in patients who are unlikely to benefit; however, these recommendations have not been consistently adopted into clinical practice. This study examines use of targeted efforts (implementation strategies) to improve implementation of the recommendations, with a goal of reducing unnecessary transfusions and improving patient outcomes in critically ill children.
Official title: Transfusion Recommendations Implemented in the PICU (TRIP)
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2024-11-30
Completion Date
2027-02-01
Last Updated
2025-08-07
Healthy Volunteers
No
Conditions
Interventions
Implementation strategies to increase use of transfusion recommendations
Five implementation strategies will be employed in this study to enhance use of the blood transfusion recommendations. These include 1) building consensus, 2) provider education, 3) identifying and empowering champions ,4) use of computerized clinical decision support tools, and 5) provide quantitative metric-based feedback. Strategies 1-3 will occur prior to initiation of CCDS tools. All patients admitted to the PICU following the date of CCDS tool initiation will be considered to be part of the post-implementation phase. The investigators will collect data from the EHR on CCDS use and conduct provider surveys and interviews following CCDS tool initiation. Surveys and interviews will be both be conducted at 6 and 12 months post-CCDS tool initiation. Process and outcomes measures will be assessed before an after use of the implementation strategies.
Locations (2)
Lucile Packard Children's Hospital, Stanford University
Palo Alto, California, United States
The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States