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NOT YET RECRUITING
NCT07112105
NA

Repetitive Transcranial Magnetic Stimulation Treatment of Stimulant Use Disorder

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

The purpose of this study is to establish a new treatment (repetitive transcranial stimulation (rTMS)) for Veterans with stimulant use disorder (SUD). Despite the large public health burden imposed by SUD, there is currently no FDA-approved or widely recognized effective somatic treatment. This placebo controlled study will test the effectiveness of rTMS in the treatment of SUD, and explore biomarkers that may guide patient selection for rTMS treatment and predict treatment response.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

106

Start Date

2026-05-01

Completion Date

2029-12-31

Last Updated

2026-04-02

Healthy Volunteers

No

Interventions

DEVICE

Repetitive transcranial magnetic stimulation (rTMS)

rTMS is a non-invasive procedure in which administering a transient magnetic field induces electrical currents in specific, targeted brain regions. The intervention (active and sham) will be administered in 30 sessions across 2 weeks. The brain region targeted is the dorsolateral prefrontal cortex.

DEVICE

Sham rTMS

Subjects randomized to sham rTMS will undergo the same procedures on the same equipment as subjects assigned to active rTMS, but no active magnetic stimulation will be delivered.

Locations (1)

VA Palo Alto Health Care System, Palo Alto, CA

Palo Alto, California, United States