Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT07112196
PHASE2/PHASE3

Visugromab in Cachexia International Trial

Sponsor: CatalYm GmbH

View on ClinicalTrials.gov

Summary

A study of how well and safely a new drug called visugromab works in people with certain kinds of cancer (including lung and bowel cancer) and unintended weight loss known as cachexia. The main questions it aims to answer are: * Does visugromab help participants put weight back on and have a better appetite? * Does visugromab help participants move more and better? * What medical problems do participants have when taking visugromab? Researchers will compare visugromab to a placebo (a look-alike substance that contains no drug). Participants will visit the hospital or clinic once every 4 weeks to receive visugromab or placebo via a drip into a vein and to undergo checkups and tests.

Official title: Adaptive, Phase 2/3, Randomized, Double-Blind Trial Investigating the Efficacy and Safety of Visugromab Versus Placebo in Patients With Cancer-associated Cachexia

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

518

Start Date

2026-04

Completion Date

2030-12

Last Updated

2026-03-30

Healthy Volunteers

No

Interventions

DRUG

Visugromab (CTL-002)

High dose

DRUG

Placebo

IV infusion

DRUG

Visugromab (CTL-002)

Medium dose

DRUG

Visugromab (CTL-002)

Low dose

Locations (1)

Mid Florida Hematology and Oncology Centers

Orange City, Florida, United States