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Visugromab in Cachexia International Trial
Sponsor: CatalYm GmbH
Summary
A study of how well and safely a new drug called visugromab works in people with certain kinds of cancer (including lung and bowel cancer) and unintended weight loss known as cachexia. The main questions it aims to answer are: * Does visugromab help participants put weight back on and have a better appetite? * Does visugromab help participants move more and better? * What medical problems do participants have when taking visugromab? Researchers will compare visugromab to a placebo (a look-alike substance that contains no drug). Participants will visit the hospital or clinic once every 4 weeks to receive visugromab or placebo via a drip into a vein and to undergo checkups and tests.
Official title: Adaptive, Phase 2/3, Randomized, Double-Blind Trial Investigating the Efficacy and Safety of Visugromab Versus Placebo in Patients With Cancer-associated Cachexia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
518
Start Date
2026-04
Completion Date
2030-12
Last Updated
2026-03-30
Healthy Volunteers
No
Conditions
Interventions
Visugromab (CTL-002)
High dose
Placebo
IV infusion
Visugromab (CTL-002)
Medium dose
Visugromab (CTL-002)
Low dose
Locations (1)
Mid Florida Hematology and Oncology Centers
Orange City, Florida, United States