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Pressure-Volume Loop Assessment in Valvular Heart Disease
Sponsor: Nantes University Hospital
Summary
The VHD PV loop study intends to assess invasive right ventricular to pulmonary artery (RV-PA) coupling in patients with valvular heart disease (VHD). Invasive RV-PA coupling is measured by using conductance catheters, the gold standard assessment for ventricular physiology. Several non-invasive parameters have been reported as surrogates for this complex physiological entity, but none of them has been tested against the gold-standard in this population. Based on this, our main objective is to assess the correlation of imaging derived RV-PA coupling in comparison to the invasive measurement.
Official title: Invasive Hemodynamic Study of Structural Heart Diseases: A Monocentric, Non-Randomized Approach
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2025-09-04
Completion Date
2027-09-04
Last Updated
2025-09-16
Healthy Volunteers
No
Interventions
Observational Invasive Hemodynamic Assessment
Collection and analysis of invasive hemodynamic data obtained through routine cardiac catheterization performed as part of standard care. No intervention is mandated by the study protocol.
Locations (1)
CHU of NANTES
Nantes, Loire Atlantique, France