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Development, Validation and Evaluation of a Deprescribing Tool
Sponsor: Indian Council of Medical Research
Summary
The goal of this clinical trial is to learn if a deprescribing tool can help in reducing prescriptions with potentially inappropriate medications (PIMs), in the Indian elderly population. The main question it aims to answer is- Can inappropriate polypharmacy in elderly patients be reduced through development and implementation of a deprescribing tool relevant to the Indian context? Researchers will compare control arm outcome parameters to see if there is a reduction in Proportion of prescriptions with at least one PIM ( Primary outcome parameter). Participating Prescribers ( Physicians) will be randomized to Control or Intervention arms. Particpating patients will not be randomized, and will receive routine consultation with a Physician who does not use the Deprescribing Tool (Control arm) or a prescriber who uses the Deprescribing tool ( Intervention Arm)
Official title: Development and Validation of a Deprescribing Tool Relevant to the Indian Context and Evaluation of Its Effectiveness in Reducing Inappropriate Polypharmacy in the Elderly
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1650
Start Date
2025-05-01
Completion Date
2026-09
Last Updated
2025-08-14
Healthy Volunteers
No
Conditions
Interventions
Deprescribing Tool
Deprescribing Tool will be used for medication review during patient consultation. The prescriber will be encouraged to refer to the tool for medication review of elderly patients aged ≥ 60 years and take deprescribing decision if indicated. Deprescribing may take place in any of the following ways- 1. Immediate discontinuation of a drug, e.g., a duplicate drug 2. Initiation of gradual tapering of a drug e.g., an anxiolytic, which is no longer indicated 3. Reduction in dose of a drug, e.g., lower dose of an NSAID for relief of symptoms of rheumatoid arthritis Only 1-3 medicines will be deprescribed at a time. Medicines with overlapping indications will not be deprescribed at the same time so it is clear which medicine is responsible if withdrawal effects occur.
Locations (2)
St. John's Medical College, Bangalore, India
Bangalore, Karnataka, India
All India Institute of Medical Sciences Bhopal
Bhopal, Madhya Pradesh, India