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A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Summary
Objective of this clinical trial: The goal of this clinical study is to evaluate whether an environmental probiotic spray can improve symptoms in adults with cat allergy-induced allergic rhinitis (AR) and allergic asthma (AA). It will also assess the safety of the probiotic spray. The main questions it aims to answer are: Does the environmental probiotic spray reduce the severity of nasal and asthma symptoms in participants? Are there any adverse effects observed in participants using the probiotic spray? Researchers will compare the environmental probiotic spray group to a placebo group (a look-alike spray containing no active ingredients) to determine if the probiotic spray is effective in managing allergic rhinitis and asthma symptoms. Participants will: Receive the environmental probiotic spray or placebo daily for 3 months Attend monthly clinic visits for checkups and assessments Undergo a final evaluation at 3 months, including symptom scoring and safety checks Key Assessments: Total Nasal Symptom Score (TNSS) for allergic rhinitis Asthma Control Test (ACT) score for allergic asthma
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-06-30
Completion Date
2027-06-30
Last Updated
2025-08-11
Healthy Volunteers
No
Interventions
Environmental Probiotic Spray Intervention
The probiotic strains include Bacillus subtilis YHX001J, Bacillus amyloliquefaciens YHX002J, and Bacillus velezensis YHX003J
Purified water spray (containing no active ingredients) as the placebo control
Purified water spray
Locations (1)
Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China