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Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors
Sponsor: Case Comprehensive Cancer Center
Summary
The purpose of this research study is to investigate whether cancer survivors have higher levels of proteins called Fatty Acid Binding Proteins as well as 12 different markers of cellular senescence than people who have never had cancer. Investigators believe that these levels may be elevated in cancer survivors as a result of their cancer and the treatments they received and may put them at higher risk for chronic conditions such as high cholesterol, diabetes, high blood pressure, and obesity. This study will also compare the levels of these proteins and inflammatory markers in the blood with different aspects of cancer treatment the survivors received. Investigators are investigating if there is a correlation between levels of these proteins and markers, the type of treatment cancer survivors received, and development of metabolic conditions.
Key Details
Gender
All
Age Range
5 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2025-11
Completion Date
2026-05
Last Updated
2025-09-30
Healthy Volunteers
No
Conditions
Interventions
Specimen #1
Specimen 1 will be collected in a 10 ml SST (serum separator tube).
Specimen #2
Specimen #2 will be collected in a 10 ml SST (serum separator tube)
Locations (1)
Case Comprehensive Cancer Center, UH Rainbow Babies & Children's Hospital
Cleveland, Ohio, United States