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The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled Trial
Sponsor: Far Eastern Memorial Hospital
Summary
The optimal medication for women with nocturia remains uncertain. This clinical trial aimed to determine the most effective medication for women with overactive bladder and nocturia. Its primary objectives were to answer the following questions: Which medication is most effective for women with nocturia? Which medication has the least effect on heart rate variability in women with nocturia?
Official title: Far Eastern Memorial Hospital
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
220
Start Date
2025-08-07
Completion Date
2028-12-31
Last Updated
2025-08-11
Healthy Volunteers
No
Conditions
Interventions
Mirabegron 25mg
Taking 25 mg mirabegron in the nighttime
Solifenacin 5 mg
Taking 5 mg solifenacin in the nighttime
Tolterodine 4 mg
Taking 5 mg tolterodine in the nighttime
Oxybutynin ER 5 mg
Taking 5 mg oxybutynin ER in the nighttime
Locations (1)
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital,
Banqiao District, New Taipei, Taiwan