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Molecular Characterization of Carbapenemase-Producing Enterobacterales
Sponsor: Sohag University
Summary
Bacterial infections with carbapenem resistant pathogens are one of the major threats in immunocompromised patients, especially among cancer patients .Furthermore, Gram negative pathogens are becoming increasingly prevalent and have become an ongoing global health concern .Emergence of Gram-negative pathogens, especially Enterobacterales that avert many of the human defense mechanisms are alarmingly increasing and most of these pathogens are resistant to many of the in-use antibiotics including carbapenems .
Official title: Molecular Characterization of Carbapenemase-Producing Enterobacterales Isolated From Clinical Samples in Egypt
Key Details
Gender
All
Age Range
4 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-09-10
Completion Date
2026-02-20
Last Updated
2025-08-11
Healthy Volunteers
No
Conditions
Interventions
Antibiotic administration
different samples were collected from patients admitted at oncology center at sohag
Molecular detection of antibiotic resistance
Molecular detection of carbapenem resistant genes: * Extraction of nucleic acid from isolated organisms by boiling. * Primers will be used for detection of carbaenem resistant genes
Locations (1)
Sohag university, Faculty of medicine
Sohag, Egypt