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Serial Assessment of Fertility Experiences
Sponsor: Children's Hospital Medical Center, Cincinnati
Summary
The SAFE study is a long-term research project that watches people with sickle cell anemia (SCA) over time. The main goal is to see how a medicine called hydroxyurea affects their growth, puberty, and ability to have children. A second goal is to see how hydroxyurea affects pregnancy outcomes, by comparing people who take the medicine to those who don't.
Official title: A Prospective Longitudinal Study of Growth, Development, Fertility and Reproductive Outcomes Among Adolescents and Young Adults With Sickle Cell Anemia With Hydroxyurea
Key Details
Gender
All
Age Range
8 Years - Any
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2023-07-10
Completion Date
2035-12-31
Last Updated
2026-02-04
Healthy Volunteers
No
Conditions
Locations (3)
Centro de Obstetricia y Ginecologia
Santo Domingo, Dominican Republic
Caribbean Institute for Health Research, University of West Indies
Kingston, Jamaica
Buganda Medical Centre
Mwanza, Tanzania