Clinical Research Directory
Browse clinical research sites, groups, and studies.
Development and Validation of RCC Predicting Model With Emulated-target Trial
Sponsor: Peking University Third Hospital
Summary
This single-center study utilizes real-world data (2012-2024) from 4700 renal cell carcinoma (RCC) patients at Peking University Third Hospital to: (1) Develop and validate a prognostic prediction model specifically for RCC patients, including those with venous tumor thrombus (VTT); (2) Compare the performance of this new model against existing RCC prediction models in both the overall RCC cohort and the VTT subgroup; (3) Employ an emulated target trial (ETT) methodology to evaluate whether risk-stratified treatment based on the prediction model (grouping patients as high/medium/low risk) improves survival outcomes (Overall Survival, Recurrence-Free Survival) and health economic outcomes (Quality-Adjusted Life-Years, Incremental Cost-Effectiveness Ratio), compared to non-stratified treatment group.
Official title: A Prognostic Prediction Model for Renal Cell Carcinoma With Venous Tumor Thrombus and Emulated-target Trial for Guiding Stratified Treatment
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
4700
Start Date
2025-08-15
Completion Date
2028-07-16
Last Updated
2025-08-12
Healthy Volunteers
No
Conditions
Locations (1)
Peking University Third Hospital
Beijing, Beijing Municipality, China