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A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and Digoxin
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Summary
The purpose of this study is to evaluate the effects of KarXT administration on the drug levels of midazolam, fexofenadine, and digoxin in healthy adult participants.
Official title: A Phase 1, 3-part, Open-label Study to Evaluate the Effects of KarXT Administration on the Pharmacokinetics of Midazolam, Fexofenadine, and Digoxin in Healthy Adult Participants
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-09-29
Completion Date
2026-04-05
Last Updated
2026-03-02
Healthy Volunteers
Yes
Conditions
Interventions
KarXT
Specified dose on specified days
Midazolam
Specified dose on specified days
Fexofenadine
Specified dose on specified days
Digoxin
Specified dose on specified days
Locations (1)
ICON - Lenexa
Lenexa, Kansas, United States