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RECRUITING
NCT07118215
PHASE1

A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and Digoxin

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the effects of KarXT administration on the drug levels of midazolam, fexofenadine, and digoxin in healthy adult participants.

Official title: A Phase 1, 3-part, Open-label Study to Evaluate the Effects of KarXT Administration on the Pharmacokinetics of Midazolam, Fexofenadine, and Digoxin in Healthy Adult Participants

Key Details

Gender

All

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-09-29

Completion Date

2026-04-05

Last Updated

2026-03-02

Healthy Volunteers

Yes

Interventions

DRUG

KarXT

Specified dose on specified days

DRUG

Midazolam

Specified dose on specified days

DRUG

Fexofenadine

Specified dose on specified days

DRUG

Digoxin

Specified dose on specified days

Locations (1)

ICON - Lenexa

Lenexa, Kansas, United States