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RECRUITING
NCT07119398
PHASE4

Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM

Sponsor: Eastern Virginia Medical School

View on ClinicalTrials.gov

Summary

Data on the optimal mode of labor induction after preterm prelabor rupture of membranes (PPROM) is lacking. Studies have shown no difference between oxytocin and misoprostol use for labor induction in this cohort (1). The preponderance of evidence from term pregnancies suggests that Foley catheter coupled with oxytocin is better than oxytocin alone, with a higher rate of delivery within 24 hours when a Foley catheter followed by oxytocin is compared to oxytocin alone. However, the use of a Foley catheter has not been evaluated in prospective studies on patients with PPROM.

Official title: Combination Oxytocin/Foley Versus Oxytocin Alone for Induction of Labor in Patients With Preterm Prelabor Rupture of Membranes

Key Details

Gender

FEMALE

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2025-07-14

Completion Date

2026-12-30

Last Updated

2025-08-13

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

Oxytocin plus Foley Catheter

Intravenous oxytocin and a transcervical Foley catheter

DRUG

Oxytocin

Intravenous oxytocin

Locations (1)

Sentara Norfolk General Hospital

Norfolk, Virginia, United States