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Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM
Sponsor: Eastern Virginia Medical School
Summary
Data on the optimal mode of labor induction after preterm prelabor rupture of membranes (PPROM) is lacking. Studies have shown no difference between oxytocin and misoprostol use for labor induction in this cohort (1). The preponderance of evidence from term pregnancies suggests that Foley catheter coupled with oxytocin is better than oxytocin alone, with a higher rate of delivery within 24 hours when a Foley catheter followed by oxytocin is compared to oxytocin alone. However, the use of a Foley catheter has not been evaluated in prospective studies on patients with PPROM.
Official title: Combination Oxytocin/Foley Versus Oxytocin Alone for Induction of Labor in Patients With Preterm Prelabor Rupture of Membranes
Key Details
Gender
FEMALE
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-07-14
Completion Date
2026-12-30
Last Updated
2025-08-13
Healthy Volunteers
No
Conditions
Interventions
Oxytocin plus Foley Catheter
Intravenous oxytocin and a transcervical Foley catheter
Oxytocin
Intravenous oxytocin
Locations (1)
Sentara Norfolk General Hospital
Norfolk, Virginia, United States