Inclusion Criteria:
* Female subjects aged ≥ 18 years.
* Histologically confirmed breast or gynecologic cancer.
* Developed neuropathic pain with the initiation of or within one month after completion of treatment with anti-neoplastic agents from the following class:
* Platinum-based drugs
* Taxanes
* Vinca alkaloids
* Pain score 4 or more on the Pain Numeric Rating Scale (PNRS).
* Score 3 or more on the Douleur Neuropathique 4 (DN-4) questionnaire.
* Persistent neuropathic pain with current use of at least one neuropathic medication.
* Subjects must have been on a stable dose of neuropathic pain medication for at least 6 weeks prior to enrollment.
\-- Note: Additional washout periods for other pain medications may be needed and will be determined by the Investigator.
* For female subjects: Negative pregnancy test or evidence of post-menopausal status. The post-menopausal status will be defined as having been amenorrheic for 12 months without an alternative medical cause. The following age-specific requirements apply:
* Women \< 50 years of age:
* Amenorrheic for ≥ 12 months following cessation of exogenous hormonal treatments; and
* Luteinizing hormone and follicle-stimulating hormone levels in the post-menopausal range for the institution; or
* Underwent surgical sterilization (bilateral oophorectomy or hysterectomy).
* Women ≥ 50 years of age:
* Amenorrheic for 12 months or more following cessation of all exogenous hormonal treatments; or
* Had radiation-induced menopause with last menses \>1 year ago; or
* Had chemotherapy-induced menopause with last menses \>1 year ago; or
* Underwent surgical sterilization (bilateral oophorectomy, bilateral salpingectomy, or hysterectomy).
* Subjects of childbearing potential must agree to use a highly effective method of contraception as described in Section 5.4.1.
* Able to provide informed consent and willing to sign an approved consent form that conforms to federal and institutional guidelines.
Exclusion Criteria:
* Evidence of recurrent breast or gynecologic cancer at the time of enrollment.
* Current or planned treatment with chemotherapy.
--Note: Other anti-cancer treatments (e.g. hormone therapy and targeted therapies) are allowed at the Investigator's discretion.
* History of seizure, epilepsy, or other conditions that would, in the opinion of the investigator, negatively impact the patient's safety or ability to participate in the study.
* Presence of neuropathic pain unrelated to systemic cancer therapy, including but not limited to: painful diabetic neuropathy, HIV-induced neuropathy, neuropathic pain from radiation therapy and underlying cancer/other medical conditions.
* Presence of implantable devices including spinal cord stimulators, dorsal root ganglion stimulators, deep brain stimulators, cochlear implants, intrathecal pain pumps, and intracranial metallic objects which are incompatible with rTMS administration in the opinion of the treating investigator.
* Subjects on medications that, in the opinion of the investigator, significantly lower seizure threshold will be excluded.
* Any condition that would, in the Investigator's judgment, contraindicate the subject's participation in the clinical study due to safety concerns or compliance with clinical study procedures.
* History of recent suicide attempt or active suicidal ideation that, in the opinion of the investigator, presents an increased risk for study participation
* Medical, psychiatric, cognitive, or other conditions that may compromise the subject's ability to understand the subject information, give informed consent, comply with the study protocol or complete the study.
* Enrollment in another study that, in the opinion of the investigator, would negatively impact study participation or cause undue burden for the subject.
