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SMC Radiation Oncology SABR Cohort for Oligometastasis
Sponsor: Samsung Medical Center
Summary
The goal of this observational study is to evaluate the efficacy and safety of stereotactic body radiotherapy (SABR) in patients with oligometastatic or oligoprogressive cancer. The main questions it aims to answer are: 1. oncologic outcomes (progression-free survival, local failure rate), 2. patient-reported outcomes, 3. physician-assessed toxicity, and 4. dynamics of circulating tumor DNA (ctDNA) for biomarker analysis.
Official title: Cohort Study for Local Stereotactic Body Radiotherapy in Patients With Oligometastatic or Oligoprogressive Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2025-05-01
Completion Date
2030-03-31
Last Updated
2025-08-13
Healthy Volunteers
No
Conditions
Interventions
Stereotactic body radiotherapy (SBRT)
Stereotactic body radiotherapy (SABR) using photon or proton beams will be delivered per standard practice (1-5 fractions).
Locations (1)
Samsung medical center
Seoul, South Korea