Clinical Research Directory

Inclusion Criteria:• Patients free from any systemic diseases that may interfer with the normal healing process. * Maxillary traumatized or cariously exposed non-vital immature anterior teeth. * Teeth don't need for post and core as a final restoration. * Radiographic evidence of an apical opening width more than 2 mm with or without periapical radiolucency. * Teeth without anatomical variations Exclusion Criteria:• Immunocompromised patients * Teeth with previous endodontic treatment. * Teeth with internal or external resorption * Radiographic evidence of root fracture. * Lack of patient and parent cooperation. * Presence of periodontal pocket depth more than 4 mm.